Adiponectin, role in insulin resistance, atherosclerosis and carcinogenesis

نویسندگان

  • I. M. JAZET
  • A. E. MEINDERS
چکیده

targets for the central regulation of body weight. CNS Neurol Disord Drug Targets 2006; 5: 263-74. 71. Nargund RP, Strack AM, Fong TM. Melanocortin-4 receptor (MC4R) agonists for the treatment of obesity. J Med Chem 2006; 49: 4035-43. 72. van den Hoek AM, Heijboer AC, Corssmit EP, Voshol PJ, Romijn JA, Havekes LM, Pijl H. PYY3-36 Reinforces Insulin Action on Glucose Disposal in Mice Fed a HighFat Diet. Diabetes 2004; 53: 1949-52. 73. van den Hoek AM, Heijboer AC, Corssmit EP, Romijn JA, Havekes LM, Pijl H. Chronic PYY3-36 treatment ameliorates insulin resistance in C57BL\6 mice on a high fat diet. Am J Physiol Endocrinol Metab, 2006, in press. 74. Foster-Schubert KE, Cummings DE. Emerging Therapeutic Strategies for Obesity. Endocr Rev 2006; 27: 799793.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

AdipoRon may be benefit for atherosclerosis prevention

Atherosclerosis has serious role in coronary arteries disease,so it is important to establish effective strategies for prevention or even treatment of atherosclerosis. Adiponectin, as one of the most abundant adipokines, has insulin sensitivity, anti-inflammatory and anti-atherogenic properties. Disturbed adiponectin actions through its receptor, (AdipoR1 and AdipoR2) may be involved in atheros...

متن کامل

Association of adiponectin gene rs2241766 polymorphism with serum adiponectin level, Insulin resistance and type 2 diabetes mellitus in an Iranian population

Introdution: Adiponectin is a peptide secreted from fat cells that plays an important role in the development of insulin resistance and type 2 diabetes. A number of single nucleotide polymorphisms in the adiponectin gene are associated with lower adiponectin expression and T2DM. The aim of this study was to determination the frequency of rs 2241766 polymorphism in adiponectin gene and its relat...

متن کامل

تعیین ارتباط بین آدیپونکتین سرم و مقاومت انسولین، در بیماران دیابت نوع 2

Background and Aim: Obesity is associated with some chronic morbidity including atherosclerosis, hypertension, and type 2 diabetes which are major components of metabolic syndrome. In the present study, association between insulin resistance and adiponectin, as an anti-inflammatory cytokine, in type 2 obese male diabetics was assessed. Materials and Methods: In this descriptive study, fasting s...

متن کامل

Adiponectin and its role in the obesity-induced insulin resistance and related complications.

It is now generally accepted that adipose tissue acts as an endocrine organ producing a number of substances with an important role in the regulation of food intake, energy expenditure and a series of metabolic processes. Adiponectin is a recently discovered protein produced exclusively by adipocytes. A number of studies have shown that obesity, insulin resistance and atherosclerosis are accomp...

متن کامل

Leptin, Ghrelin, Adiponectin, Homocysteine and Insulin Resistance Related to Polycystic Ovary Syndrome

The relationship between leptin, adiponectin, ghrelin, homocysteine, insulin resistance and other biochemical factors in women with polycystic ovary syndrome (PCOS) is controversial. We review how the expanded role of these factors in reproduction might impact our understanding of PCOS. For purposes of our review, we accessed the PUBMED database during the past 10 years. Our review confirms tha...

متن کامل

Association of adiponectin level with biochemical variables and insulin resistance in patients with non-alcoholic fatty liver disease in an Iranian population

Background: Non-alcoholic fatty liver disease is one of the most important chronic liver disorders worldwide. Adipokines are polypeptide hormones that participate in the pathogenesis of non-alcoholic fatty liver disease. Adiponectin is an adipokine that stimulates fatty acid oxidation in muscle and plays a role in the development of insulin sensitivity. This study aimed to investigate the assoc...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2007